WebSIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed … WebSiglecs are cell surface lectins that recognize sialic acids and are primarily expressed in hematopoietic cells. Previous studies showed that some Siglecs regulate macrophage …
CD170 (Siglec F) Monoclonal Antibody (1RNM44N), PE …
WebSiglecs (sialic acid-binding, Ig-like lectins) are a family of single-pass transmembrane cell surface proteins found predominantly on leucocytes. Their unique structural … WebOct 7, 2016 · Intestinal microfold (M) cells are epithelial cells primarily present on Peyer's patches (PPs) in the small intestine. The ability of M cells to shuttle antigens into the PP … grant writing classes maine
Alexa Fluor® 647 anti-mouse CD170 (Siglec-F) Antibody
WebJan 17, 2024 · Enables monosaccharide binding activity and sialic acid binding activity. Involved in regulation of endocytosis. Located in lysosome. Orthologous to several human … WebThe important finding that deleting Mo-AMs within an injured lung can lessen the severity of fibrosis represents a significant advance in the field (14 and 15).Although many groups have shown that mice with systemic monocytopenia (i.e., mice given intravenous liposomal clodronate, CCR2 −/− mice, and CEPBδ −/− mice) are protected against fibrosis (8, 16, 17), … WebJun 22, 2005 · Analysis of sialoside specificity of Siglec-F. To understand the structural requirement of 6′-sulfo-sLe X that confers increased affinity to Siglec-F, we further verified the glycan array results by reverse assay using various sialylated oligosaccharides coupled to polyacrylamide backbones (sialoside-PAA probes) and immobilized Siglec-F-Fc chimera. grant writing classes online for nonprofits