Tendamistat
WebJul 21, 1995 · Tendamistat as a scaffold for conformationally constrained phage peptide libraries. The alpha-amylase inhibitor Tendamistat (Hoe-467), a 74 amino acid beta … Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆
Tendamistat
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WebJan 1, 2006 · Tendamistat, a small disulfide-bonded β-sheet protein, and its three single/double-disulfide mutants are investigated by using a modified Gō-like model, aiming to understand the folding mechanism of disulfide-bonded protein as well as the effects of removal of disulfide bond on the folding process.Our simulations show that tendamistat … WebAmyAc_bac_euk_AmyA. cd11317 (153-401): Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase) AmyAc_family. cl38930 (10-104): The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on …
WebThe active site of tendamistat coincides with the largest surface patch accessible to the probe. A strong hydration of protein N and C termini can also be suggested by this structural approach, as these locations exhibit reduced paramagnetic pertubations. Provided that the solution structure is known, the use of this paramagnetic probe seems to ... WebTendamistat (HOE 467), a potent inhibitor of the human pancreatic α-amylase, is an acidic protein of 74 amino acids (Vértesy et al., 1984). The inhibitor gene was cloned from an …
WebPubMed WebTendamistat is a strong inhibitory protein of porcine pancreatic alpha-amylase (PPA) with a K(i) value of 0.2 nM. To develop potent alpha-amylase inhibitors, we synthesized six odd-length cyclic peptides (5-15 residues) and four even-length cyclic peptides (10 and 12 residues) having the inhibitory sequence of tendamistat.
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WebJul 22, 1997 · The role of preformed correct side chain interactions, such as disulfide bonds, on protein folding kinetics is still not well understood. We investigated the effect of disulfide bond replacements on folding and stability of the small β-sheet protein tendamistat. Tendamistat folds very fast (τ = 10 ms at pH 7 in water) and without detectable … tara air nepal newsWebOct 17, 2024 · A common repetitive use injury. Tendonitis (also spelled tendinitis) is inflammation or irritation of a tendon, the flexible, fibrous cords that connect muscles to … tara akbaripourWebJan 4, 2000 · Tendamistat was a gift from Klaus Koller (Hoechst, Frankfurt, Germany). Purity was checked by MS and reversed-phase HPLC and exceeded 99%. Ultra-pure … tara akdoratara akhiya ke kajal hamar jaan le gailWebTendinitis is an inflammation of tendons. Tendons join muscles to bones. Tendinitis can occur in the fingers, thumbs, wrists, elbows, knees, and thighs. The most likely cause is … tara akbasWebEngels’ Forschungsinteresse galt überwiegend der Nucleotidchemie; insbesondere der Synthese modifizierter Oligonucleotide und deren Analytik und möglichen therapeutischen Anwendungen sowie der Funktion von Parvulustat und Tendamistat. Joachim Engels hat über 300 wissenschaftliche Publikationen und Patente verfasst. tara akhshiWebFeb 5, 1992 · The specific stability of tendamistat is similar to that of modified bovine pancreatic trypsin inhibitor, with only two of the native three disulfide bridges intact. This … tara akers warsaw in